Since 1911 MACHEREY-NAGEL stands for high quality, innovation and reliability in chemical and biomolecular analysis. Friendly expert advice for our highly valued customers as well as outstanding product quality have been the cornerstones of our corporate success for more than 100 years. MACHEREY-NAGEL is a family-owned company run by the fourth generation. As one of today’s leading manufacturers of products for analytical chemistry and life science we offer a broad range of products for Filtration, Rapid Tests, Water Analysis, Chromatography and Bioanalysis.
Headquarters and manufacturing site in Düren (Germany), further location in Oensingen (Switzerland)
MACHEREY-NAGEL has grown from a pioneer in chromatography to a full-range supplier of laboratory consumables. We supply laboratories all over the world with HPLC, GC and SPE columns, TLC plates and sheets, syringe filters or suitable vials and closures. Our philosophy includes personal and competent support as well as outstanding product quality. We have the demand to fulfill the customer’s individual needs and offer optimal and reliable solutions for your lab work in method development and routine analysis.
1. Solid phase extraction
Our CHROMABOND® QC policy
- Highest production standard – our facilities are EN ISO 9001:2008 certified
- All products are individually tested to meet our strict quality specifications, ensuring our outstanding product reproducibility, reliability and performance
- Perfect reproducibility from lot-to-lot and within every single batch:
> Careful attention to particle size distribution and pore diameters assures consistent column flow
> Chemical reproducibility is guaranteed by strict quality control throughout manufacturing - Each product is supplied with a certificate of analysis stating the results of internal examinations and quality control
Solid Phase Extraction Demonstration
Design of columns, cartridges and 96-well plates
CHROMABOND® summary of MN phases
|
CHROMABOND® |
Matrix |
Modification / Application |
|
Reversed phases |
||
|
HR-X |
PS/DVB |
|
|
Easy |
PS/DVB |
polar, bifunctional |
|
HR-P |
PS/DVB |
|
|
PS-RP |
PS/DVB |
removal of organic components |
|
C18 ec |
silica |
octadecyl, endcapped |
|
C18 ec f |
silica |
as above, fast flow |
|
C18 |
silica |
octadecyl, not endcapped |
|
C18 f |
silica |
as above, fast flow |
|
C18 Hydra |
silica |
octadecyl, not endcapped, for polar analytes |
|
C8 |
silica |
octyl |
|
C4 |
silica |
butyl |
|
C2 |
silica |
dimethyl |
|
C6H11 ec |
silica |
cyclohexyl, endcapped |
|
C6H5 |
silica |
phenyl |
|
Normal phases |
||
|
SiOH |
silica |
unmodified |
|
NH2 |
silica |
aminopropyl |
|
OH (Diol) |
silica |
diol |
|
CN |
silica |
cyano |
|
HILIC |
silica |
zwitterionic ammonium-sulfonic acid modification |
|
Alox A |
aluminum oxide |
acidic |
|
Alox N |
aluminum oxide |
neutral |
|
Alox B |
aluminum oxide |
basic |
|
Florisil® |
magnesium silicate |
|
|
PA |
Polyamide 6 |
|
|
Ion exchangers |
||
|
SA |
silica |
benzenesulfonic acid cation exchanger (SCX) |
|
SB |
silica |
quaternary ammonium anion exchanger (SAX) |
|
PCA |
silica |
propylcarboxylic acid cation exchanger (WCX) |
|
PSA** |
silica |
propylsulfonic acid cation exchanger |
|
HR-XC |
PS/DVB |
strong mixed mode cation exchanger for basic analytes (MCX) |
|
HR-XA |
PS/DVB |
strong mixed mode anion exchanger for acidic analytes (MAX) |
|
HR-XCW |
PS/DVB |
weak mixed mode cation exchanger for basic analytes (WCX) |
|
HR-XAW |
PS/DVB |
weak mixed mode anion exchanger for acidic analytes (WAX) |
|
PS-OH– |
PS/DVB |
strong anion exchanger in OH– form |
|
PS-H+ |
PS/DVB |
strong cation exchanger in H+ form |
|
PS-Mix |
PS/DVB |
mixture of PS-OH– and PS-H+ |
|
PS-Ag+ |
PS/DVB |
strong cation exchanger in Ag+ form |
|
PS-Ba2+ |
PS/DVB |
strong cation exchanger in Ba2+ form |
|
Phases for special applications |
||
|
Drug |
silica |
bifunctional C8/SA, for enrichment of drugs from urine |
|
Drug II |
silica |
bifunctional C8/SB, for extraction of THC and derivatives and of acidic analytes from biological fluids |
|
Tetracycline |
silica |
special octadecyl phase, for enrichment of tetracyclines |
|
HR-P-AOX |
PS/DVB |
for extraction of AOX from water (DIN 38409 – H22) |
|
C18 PAH |
silica |
special octadecyl phase, for enrichment of PAHs from water |
|
NH2/C18 |
silica |
combination phase for enrichment of PAHs from water |
|
CN/SiOH |
silica |
combination phase for enrichment of PAHs from soil |
|
Na2SO4/Florisil® |
combination phase for extraction of hydrocar- bons from water (DIN H-53 / ISO DIS 9377-4) |
|
|
NAN |
silica / AgNO3 + Na2SO4 |
combination phase for enrichment of PCBs from sludge |
|
SA/SiOH |
silica |
combination phase for enrichment of PCBs from waste oil |
|
SiOH-H2SO4/SA |
silica |
combination phase, used together with SiOH for enrichment of PCB from oil |
|
QuEChERS / Diamino |
silica |
primary and secondary amine functions (PSA), for determination of pesticides in food samples (QuEChERS method) |
|
ABC18 |
silica |
octadecyl, with ion exchange functions, for acrylamide analysis |
|
Carbon A |
activated carbon |
determination of acrylamide from water according to DIN 38413-6 |
|
PL |
specially developed SPE phase for the preparation of bioanalytical samples |
|
|
Dry |
Na2SO4 |
for drying organic samples |
|
PTL/PTS |
special membrane |
phase separation |
|
XTR |
kieselguhr |
liquid-liquid extraction |
* Phases which provide a similar selectivity based on chemical or physical properties (list not complete)
** For primary and secondary amine functions see QuEChERS / Diamino
CHROMABOND® QuEChERS special silica phase for determination of pesticides in food samples
